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Jaime E. Ramírez-Vick, Ph. D.
Professor
Ph.D. Arizona State University

Office S-604
Mayagüez, PR 00680
(787) 832-4040, Ext. 5720
E-Mail:
jaimee.ramirez@upr.edu 

Professional Experience

10/09-Pres     Chair/Assoc Chair, Engineering Science & Materials

                     Department,  University of Puerto Rico, Mayagüez, PR

07/11-Pres     Adjunct Professor, Chemical Engineering Department,

                     University of Puerto Rico, Mayagüez, PR

07/07-Pres     Professor, Department of Engineering Science & Materials,  

                     University of Puerto Rico, Mayagüez, PR

04/09-Pres     Adjunct Professor, Weldon School of Biomedical Engineering,

                     Purdue University, West Lafayette, IN

01/02-06/07   Associate Professor, General Engineering Department,

                     University of Puerto Rico, Mayagüez, PR
05/01-06/06   President, Daedalus BioTechnologies, Mayagüez, PR
04/00-04/01   Chief Technology Officer, Genetic Profiling Systems, Berkeley, CA
01/99-03/00   Director of Technology, Iris Biotechnologies, Inc., Santa Clara, CA
07/88-12/88   Postdoctoral Fellow, Cancer Center,
                     University of California, San Francisco, CA
11/97-06/98   Lawrence Postdoctoral Fellow,
                     Lawrence Berkeley National Laboratory, Berkeley, CA

Professional Preparation

  • Postdoctorate, Cancer Genetics, Cancer Center, University of California, San Francisco, CA
  • Postdoctorate, Lawrence Berkeley National Laboratory, Berkeley, CA
  • Ph.D., Chemical Engineering, 1997, Arizona State University, Tempe, AZ
  • M.S., Chemical Engineering, 1989, University of Puerto Rico, Mayagüez, PR
  • B.S., Chemical Engineering, 1985, University of Puerto Rico, Mayagüez, PR

Selected Publications

Book

  • García, AA, MR Bonen, J Ramírez-Vick, M Sadaka, and A Vuppu, "Bioseparation Process Science," Blackwell Science (1999).

Proceedings (Last 3 years)

  • CY Acevedo-Morantes, MT Acevedo-Morantes, D Suleiman-Rosado, JE Ramírez-Vick, "Evaluation of the Cytotoxic Effect of Liposome-Encapsulated Camptothecin on MCF7 Breast Cancer Cells," American Association of Pharmaceutical Scientists Proceedings, November 10-14, 2013. 

  • M Lluberes, J Seguel, JE Ramírez-Vick, “Markov Model Checking of Probabilistic Boolean Networks Representations of Genes,” International Conference on Bioinformatics & Computational Biology, BioComp 2011 Proceedings, July 18-21, 2011.

  • C Rodriguez-Martinez, P Joshi, JL Vera, JE Ramirez-Vick, O Perales, SP Singh, “Cytotoxic studies of PEG functionalized ZnO Nanoparticles on MCF-7 cancer cells,” NSTI-Nanotech 2011 3:420-423, 2011.

  • N Palomera, M Balaguera, MS Tomar, JE Ramírez-Vick, S. Arya, SP Singh, “Zinc Oxide Nanorod Films for Electrochemical Urea Biosensor,” MRS Spring 2011 Proceedings, April 25-29, 2011.

  • M Alvarado-Velez, DM Rivera-Chacon, CY Acevedo-Morantes, SP Singh, E Gultepe, D Nagesha, S Sridhar, JE Ramirez-Vick, “Effects of fibronectin and vitronectin on human fetal osteoblast cell attachment and proliferation on nanostructured titania surfaces,” Meeting Abstract: 414-BIOT,   241st National Meeting and Exposition of the American-Chemical-Society (ACS) Anaheim, CA March 27-31, 2011.

  • P Joshi, S Chakraborti, JE Ramirez-Vick, ZA Ansaria, V Shanker, P Chakrabarti, SP Singh, Anti-Tumor Chloroquine-Gold Nanocomposites and their Binding Interaction with Bovine Serum Albumin: Biophysical and Biochemical Aspects of Protein Binding,” Materials Research Society Symposium Proceedings 1316:92-97, 2011.

  • N Palomera, M Balaguera, SK Arya, S Hernandez, MS Tomar, JE Ramírez-Vick, SP Singh. Zinc oxide nanorod films for electrochemical urea biosensor. Materials Research Society Symposium Proceedings 1355:54-59, 2011.  

Articles (Last 3 years)

  • N Palomera, M Balaguera, SK Arya, S Hernandez, M. Tomar, JE Ramirez-Vick and SP Singh, " Zinc Oxide Nanorods Modified Indium Tin Oxide Surface Based Amperometric Urea Biosensor," Journal of Nanoscience and Nanotechnology, 11(8):6683- 6689 (2011).
  • N Palomera, JL. Vera, E Meléndez, JE Ramirez-Vick, M. Tomar, SK Arya and SP Singh, "Redox Active Poly(pyrrole-N-ferrocene-pyrrole) Copolymer-Based Mediator-Free Biosensors," Journal of Electroanalytical Chemistry, 658(1-2):33-37 (2011).
  • CY Acevedo-Morantes, PG Caceres-Valencia, RA Irizarry-Ortiz,  SP Singh, JE Ramirez-Vick,  "Combinatorial Metal Oxide Nanoscaffolds and its Influence in Osteoblast Cell Adhesion," J Applied Physics, 111(10):102810-102817  (2012).
  • P Joshi, S Chakraborti, P Chakrabarti, ZA Ansari,  JE Ramirez-Vick, SP Singh, and V Shanker, “Anti-Tumor Chloroquine-Gold Nanocomposites and their Binding Interaction with Bovine Serum Albumin: Biophysical and Biochemical Aspects of Protein Binding,” Colloids and Surfaces B: Biointerfaces, 95:195-200 (2012).
  • JE Ramirez-Vick, “Nanostructured ZnO for Electrochemical Biosensors,” Biosens Bioelectron, 3(2):e109  (2012).

  • SK Arya, S Sahab, JE Ramirez-Vick, V Guptab, S Bhansalia, SP Singh, “Recent Advances in ZnO Nanostructures and Thin Films for Biosensor Applications,” Analytica Chimica Acta, 737:1-21 (2012).

  • CY Acevedo-Morantes, E Meléndez, SP Singh, JE Ramírez-Vick, "Cytotoxicity and Reactive Oxygen Species Generated by Ferrocenium and Ferrocene on MCF7 and MCF10A Cell Lines," J Cancer Sci Ther, 4(9):271-275 (2012).

  • M Alvarado-Velez, DM Rivera-Chacon, CY Acevedo-Morantes, SP Singh, E Gultepe, D Nagesha, S Sridhar, JE Ramirez-Vick, “Effect of fibronectin and vitronectin on human fetal osteoblast cell attachment, and proliferation on nanostructured titanium surfaces,” J Biomed Nanotechnol, 9(6):1-6 (2013).

  • CY Acevedo-Morantes, MT Acevedo-Morantes, D Suleiman-Rosado, SP Singh, JE Ramírez-Vick, "Evaluation of the Cytotoxic Effect of Camptothecin Solid Lipid Nanoparticles on MCF7 cells," Drug Delivery, 20(8):338-48 (2013). 

  • JE Ramirez-Vick, “Biophysical Stimulation for Bone Regeneration,” JSM Biotech Biomed Eng, 1(2):1014-1016 (2013).  

  • L Polo-Corrales, M Latorre-Esteves, JE Ramirez-Vick, “Scaffold design for bone regeneration,” J Nanosci Nanotech, 14(1):1-42 (2014).  

  • X Narváez-Pita, C Ortega-Zuniga, CY Acevedo-Morantes, B Pastrana, J Olivero-Verbel, JE Ramírez-Vick, E Meléndez, "Water soluble molybdenocene complexes: Synthesis, cytotoxic activity and binding studies to ubiquitin by fluorescence spectroscopy, circular dischroism and molecular modeling," J Inorg Biochem, 132(3):77-91 (2014).

  • MT Acevedo–Morantes, JE Ramirez-Vick, “Impregnation of Pharmaceutical Drugs with Supercritical Fluid Technology,” In: Supercritical Fluids: Fundamentals, Properties and Applications. PF Arce and M Aznar Eds. Nova Science Publishers, Hauppauge, NY, (2014)

Patents

  • Ramírez-Vick, JE, "Reversible immobilization of ligands onto metal surfaces, their preparation and use in biochemical applications," WO 00/70345 A1 (2000).
  • Ramírez-Vick, JE, "Reversible immobilization of ligands onto metal surfaces, their preparation and use in biochemical applications," AU 050172A5 (2000).
  • Ramírez-Vick, JE, "Method for increasing the hybridization rate of nucleic acids," WO 00/73506 A1 (2000).
  • Ramírez-Vick, JE, "Hybridization of target DNA with immobilized nucleic acid analogs," WO 01/01144 A2 (2001).
  • Ramírez-Vick, JE, "Reversible immobilization of ligands onto metal surfaces, their preparation and use in biochemical applications," EPO 00932451.8-2404-US0013348 (2002).
  • Ramírez-Vick, JE, "Method for increasing the hybridization rate of nucleic acids," EPO 00937982.7-1222 (2002).
  • Ramírez-Vick, JE, "Hybridization of target DNA with immobilized nucleic acid analogs," EPO 00948560.8-2404-US0018881 (2002).
  • Ramírez-Vick, JE, "Method for increasing the hybridization rate of nucleic acids," EP 1 206 572 B1 (2002).
  • Ramírez-Vick, JE, "Hybridization of target DNA with immobilized nucleic acid analogs," EP 1 234 82 (2002).
  • Ramírez-Vick, JE, "Reversible immobilization of ligands onto metal surfaces, their preparation and use in biochemical applications," CA 2 409 442 (2002).
  • Ramírez-Vick, JE, "Method for increasing the hybridization rate of nucleic acids," CA 2 409 523 (2002).
  • Ramírez-Vick, JE, and S Chin, "Magnetic field-enhanced hybridization of target molecules to immobilized probes," US 6,852,493 B2 (2005).
  • Ramírez-Vick, JE, "Reversible binding of molecules to metal substrates through affinity interactions," US 7,108,971 B2 (2006).

Synergistic Activities

  • Resource Center for Science and Engineering, University of Puerto Rico, Governing Board, Founding Member, 2014-Present
  • Institutional Biosafety Committee, University of Puerto Rico at Mayagüez – Founding Chairman, 2003-Present
  • Institutional Review Board, University of Puerto Rico at Mayagüez – Member, 2008-2010
  • Industrial Biotechnology Program, University of Puerto Rico at Mayagüez – Steering Committee, 2002-2005
  • Ph.D. Program in Biotechnology, University of Puerto Rico at Mayagüez – Steering Committee, 2002-2004
  • Puerto Rico TechnoEconomic Corridor - Biotechnology Cluster Founding Think Tank Member, 2001-Present

Professional Activities

  • Editorial Board

1) Journal of Biosensors & Bioelectronics, 2) Journal of Biochips & Tissue Chips, 3) Journal of Advances in Biosensors and Bioelectronics, 4) Frontiers in Sensors, 5) JSM Biotechnology & Biomedical Engineering, 6) Austin Journal of Biomedical Engineering , 7) Advanced Science, Engineering and Medicine, 8) Journal of Cancer Science & Therapy.

  • Editor

1) BioNanoScience Journal, 2) International Journal of Nanotechnology, 3) ACS Applied Materials & Interfaces, 4) Bioorganic & Medicinal Chemistry Letters, 5) Nanomedicine, 6) European Journal of Nanomedicine, 7) Bio-Medical Materials and Engineering, 8) European Journal of Medicinal Chemistry, 9) Colloids and Surfaces B: Biointerfaces, 10) Drug Delivery, 11) Nature Cell Death & Disease.

  • NIH Peer Review Panel

Ad Hoc Member of the Biomaterials and Biointerfaces Study Section

  • NIH Integrated Review Group

Ad Hoc Member of the Biological Chemistry and Macromolecular Biophysics            

Ad Hoc Member of the Interdisciplinary Molecular Sciences and Training

 




Telephone: (787) 832-4040, Extension: 3336, 2398
Fax: (787) 265-3816
email: ciym@uprm.edu
Department of Engineering Science and Materials,
Stefani Building, Office 216
Call Box 9000, Mayagüez PR 00681-9000