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Jaime E. Ramírez-Vick, Ph. D.
Professor
Ph.D. Arizona State University

Office S-604
Mayagüez, PR 00680
(787) 832-4040, Ext. 5720
E-Mail:
jaimee.ramirez@upr.edu 

Professional Experience

10/09-Pres     Chair/Assoc Chair, Engineering Science & Materials

                     Department,  University of Puerto Rico, Mayagüez, PR

07/11-Pres     Adjunct Professor, Chemical Engineering Department,

                     University of Puerto Rico, Mayagüez, PR

07/07-Pres     Professor, Department of Engineering Science & Materials,  

                     University of Puerto Rico, Mayagüez, PR

04/09-Pres     Adjunct Professor, Weldon School of Biomedical Engineering,

                     Purdue University, West Lafayette, IN

01/02-06/07   Associate Professor, General Engineering Department,

                     University of Puerto Rico, Mayagüez, PR
05/01-06/06   President, Daedalus BioTechnologies, Mayagüez, PR
04/00-04/01   Chief Technology Officer, Genetic Profiling Systems, Berkeley, CA
01/99-03/00   Director of Technology, Iris Biotechnologies, Inc., Santa Clara, CA
07/88-12/88   Postdoctoral Fellow, Cancer Center,
                     University of California, San Francisco, CA
11/97-06/98   Lawrence Postdoctoral Fellow,
                     Lawrence Berkeley National Laboratory, Berkeley, CA

Professional Preparation

  • Postdoctorate, Cancer Genetics, Cancer Center, University of California, San Francisco, CA
  • Postdoctorate, Lawrence Berkeley National Laboratory, Berkeley, CA
  • Ph.D., Chemical Engineering, 1997, Arizona State University, Tempe, AZ
  • M.S., Chemical Engineering, 1989, University of Puerto Rico, Mayagüez, PR
  • B.S., Chemical Engineering, 1985, University of Puerto Rico, Mayagüez, PR

Selected Publications

Book

  • García, AA, MR Bonen, J Ramírez-Vick, M Sadaka, and A Vuppu, "Bioseparation Process Science," Blackwell Science (1999).

Proceedings (Last 3 years)

  • M Lluberes, J Seguel, JE Ramírez-Vick, “Markov Model Checking of Probabilistic Boolean Networks Representations of Genes,” International Conference on Bioinformatics & Computational Biology, BioComp 2011 Proceedings, July 18-21, 2011.

  • C Rodriguez-Martinez, P Joshi, JL Vera, JE Ramirez-Vick, O Perales, SP Singh, “Cytotoxic studies of PEG functionalized ZnO Nanoparticles on MCF-7 cancer cells,” NSTI-Nanotech 2011 3:420-423, 2011.

  • N Palomera, M Balaguera, MS Tomar, JE Ramírez-Vick, S. Arya, SP Singh, “Zinc Oxide Nanorod Films for Electrochemical Urea Biosensor,” MRS Spring 2011 Proceedings, April 25-29, 2011.

  • M Alvarado-Velez, DM Rivera-Chacon, CY Acevedo-Morantes, SP Singh, E Gultepe, D Nagesha, S Sridhar, JE Ramirez-Vick, “Effects of fibronectin and vitronectin on human fetal osteoblast cell attachment and proliferation on nanostructured titania surfaces,” Meeting Abstract: 414-BIOT,   241st National Meeting and Exposition of the American-Chemical-Society (ACS) Anaheim, CA March 27-31, 2011.

  • P Joshi, S Chakraborti, JE Ramirez-Vick, ZA Ansaria, V Shanker, P Chakrabarti, SP Singh, Anti-Tumor Chloroquine-Gold Nanocomposites and their Binding Interaction with Bovine Serum Albumin: Biophysical and Biochemical Aspects of Protein Binding,” Materials Research Society Symposium Proceedings 1316:92-97, 2011.

  • N Palomera, M Balaguera, SK Arya, S Hernandez, MS Tomar, JE Ramírez-Vick, SP Singh. Zinc oxide nanorod films for electrochemical urea biosensor. Materials Research Society Symposium Proceedings 1355:54-59, 2011.  

  • CY Acevedo-Morantes, MT Acevedo-Morantes, D Suleiman-Rosado, JE Ramírez-Vick, "Evaluation of the Cytotoxic Effect of Liposome-Encapsulated Camptothecin on MCF7 Breast Cancer Cells," American Association of Pharmaceutical Scientists Proceedings, November 10-14, 2013. 

Articles (Last 3 years)

  • N Palomera, M Balaguera, SK Arya, S Hernandez, M. Tomar, JE Ramirez-Vick and SP Singh, " Zinc Oxide Nanorods Modified Indium Tin Oxide Surface Based Amperometric Urea Biosensor," Journal of Nanoscience and Nanotechnology, 11(8):6683- 6689 (2011).
  • N Palomera, JL. Vera, E Meléndez, JE Ramirez-Vick, M. Tomar, SK Arya and SP Singh, "Redox Active Poly(pyrrole-N-ferrocene-pyrrole) Copolymer-Based Mediator-Free Biosensors," Journal of Electroanalytical Chemistry, 658(1-2):33-37 (2011).
  • CY Acevedo-Morantes, PG Caceres-Valencia, RA Irizarry-Ortiz,  SP Singh, JE Ramirez-Vick,  "Combinatorial Metal Oxide Nanoscaffolds and its Influence in Osteoblast Cell Adhesion," J Applied Physics, 111(10):102810-102817  (2012).
  • P Joshi, S Chakraborti, P Chakrabarti, ZA Ansari,  JE Ramirez-Vick, SP Singh, and V Shanker, “Anti-Tumor Chloroquine-Gold Nanocomposites and their Binding Interaction with Bovine Serum Albumin: Biophysical and Biochemical Aspects of Protein Binding,” Colloids and Surfaces B: Biointerfaces, 95:195-200 (2012).
  • JE Ramirez-Vick, “Nanostructured ZnO for Electrochemical Biosensors,” Biosens Bioelectron, 3(2):e109  (2012).

  • SK Arya, S Sahab, JE Ramirez-Vick, V Guptab, S Bhansalia, SP Singh, “Recent Advances in ZnO Nanostructures and Thin Films for Biosensor Applications,” Analytica Chimica Acta, 737:1-21 (2012).

  • CY Acevedo-Morantes, E Meléndez, SP Singh, JE Ramírez-Vick, "Cytotoxicity and Reactive Oxygen Species Generated by Ferrocenium and Ferrocene on MCF7 and MCF10A Cell Lines," J Cancer Sci Ther, 4(9):271-275 (2012).

  • M Alvarado-Velez, DM Rivera-Chacon, CY Acevedo-Morantes, SP Singh, E Gultepe, D Nagesha, S Sridhar, JE Ramirez-Vick, “Effect of fibronectin and vitronectin on human fetal osteoblast cell attachment, and proliferation on nanostructured titanium surfaces,” J Biomed Nanotechnol, 9(6):1-6 (2013).

  • CY Acevedo-Morantes, MT Acevedo-Morantes, D Suleiman-Rosado, SP Singh, JE Ramírez-Vick, "Evaluation of the Cytotoxic Effect of Camptothecin Solid Lipid Nanoparticles on MCF7 cells," Drug Delivery, 20(8):338-48 (2013). 

  • JE Ramirez-Vick, “Biophysical Stimulation for Bone Regeneration,” JSM Biotech Biomed Eng, 1(2):1014-1016 (2013).  

  • L Polo-Corrales, M Latorre-Esteves, JE Ramirez-Vick, “Scaffold design for bone regeneration,” J Nanosci Nanotech, 14(1):1-42 (2014).  

  • X Narváez-Pita, C Ortega-Zuniga, CY Acevedo-Morantes, B Pastrana, J Olivero-Verbel, JE Ramírez-Vick, E Meléndez, "Water soluble molybdenocene complexes: Synthesis, cytotoxic activity and binding studies to ubiquitin by fluorescence spectroscopy, circular dischroism and molecular modeling," J Inorg Biochem, 132(3):77-91 (2014).

  • MT Acevedo–Morantes, JE Ramirez-Vick, “Impregnation of Pharmaceutical Drugs with Supercritical Fluid Technology,” In: Supercritical Fluids: Fundamentals, Properties and Applications. PF Arce and M Aznar Eds. Nova Science Publishers, Hauppauge, NY, (2014)

  • WI Perez-Mercado, Y Soto-Echevarria, JE Ramirez-Vick, E Melendez-Martinez, “Nanostructured gold dsDNA sensor for early detection of breast cancer by beta protein 1 (BP1),” Anal Bioanal Chem, submitted (2014).

Patents

  • Ramírez-Vick, JE, "Reversible immobilization of ligands onto metal surfaces, their preparation and use in biochemical applications," WO 00/70345 A1 (2000).
  • Ramírez-Vick, JE, "Reversible immobilization of ligands onto metal surfaces, their preparation and use in biochemical applications," AU 050172A5 (2000).
  • Ramírez-Vick, JE, "Method for increasing the hybridization rate of nucleic acids," WO 00/73506 A1 (2000).
  • Ramírez-Vick, JE, "Hybridization of target DNA with immobilized nucleic acid analogs," WO 01/01144 A2 (2001).
  • Ramírez-Vick, JE, "Reversible immobilization of ligands onto metal surfaces, their preparation and use in biochemical applications," EPO 00932451.8-2404-US0013348 (2002).
  • Ramírez-Vick, JE, "Method for increasing the hybridization rate of nucleic acids," EPO 00937982.7-1222 (2002).
  • Ramírez-Vick, JE, "Hybridization of target DNA with immobilized nucleic acid analogs," EPO 00948560.8-2404-US0018881 (2002).
  • Ramírez-Vick, JE, "Method for increasing the hybridization rate of nucleic acids," EP 1 206 572 B1 (2002).
  • Ramírez-Vick, JE, "Hybridization of target DNA with immobilized nucleic acid analogs," EP 1 234 82 (2002).
  • Ramírez-Vick, JE, "Reversible immobilization of ligands onto metal surfaces, their preparation and use in biochemical applications," CA 2 409 442 (2002).
  • Ramírez-Vick, JE, "Method for increasing the hybridization rate of nucleic acids," CA 2 409 523 (2002).
  • Ramírez-Vick, JE, and S Chin, "Magnetic field-enhanced hybridization of target molecules to immobilized probes," US 6,852,493 B2 (2005).
  • Ramírez-Vick, JE, "Reversible binding of molecules to metal substrates through affinity interactions," US 7,108,971 B2 (2006).

Synergistic Activities

  • Resource Center for Science and Engineering, University of Puerto Rico, Governing Board, Founding Member, 2014-Present
  • Institutional Biosafety Committee, University of Puerto Rico at Mayagüez – Founding Chairman, 2003-Present
  • Institutional Review Board, University of Puerto Rico at Mayagüez – Member, 2008-2010
  • Industrial Biotechnology Program, University of Puerto Rico at Mayagüez – Steering Committee, 2002-2005
  • Ph.D. Program in Biotechnology, University of Puerto Rico at Mayagüez – Steering Committee, 2002-2004
  • Puerto Rico TechnoEconomic Corridor - Biotechnology Cluster Founding Think Tank Member, 2001-Present

Professional Activities

  • Editorial Board

1) Advanced Science, 2) Advances in Materials, 3) Engineering and Medicine, 4) Austin Journal of Biomedical Engineering, 5) Frontiers in Sensors, 6) Journal of Advances in Biosensors and Bioelectronics, 7) Journal of Biochips & Tissue Chips, 8) Journal of Biomedical Engineering and Research, 9) Journal of Biosensors & Bioelectronics, 10) JSM Biotechnology & Biomedical Engineering, 11) Journal of Cancer Science & Therapy.

  • Editor

1) ACS Applied Materials & Interfaces, 2) Bio-Medical Materials and Engineering, 3) BioNanoScience Journal, 4) Bioorganic & Medicinal Chemistry Letters, 5) Bone, 6) Colloids and Surfaces B: Biointerfaces, 7) Drug Delivery, 8) European Journal of Medicinal Chemistry, 9) European Journal of Nanomedicine, 10) International Journal of Nanotechnology, 11) Nanomedicine, 12) Nature Cell Death & Disease.

  • NIH Peer Review Panel

Ad Hoc Member of the Biomaterials and Biointerfaces Study Section

  • NIH Integrated Review Group

Ad Hoc Member of the Biological Chemistry and Macromolecular Biophysics            

Ad Hoc Member of the Interdisciplinary Molecular Sciences and Training

 




Telephone: (787) 832-4040, Extension: 3336, 2398
Fax: (787) 265-3816
email: ciym@uprm.edu
Department of Engineering Science and Materials,
Stefani Building, Office 216
Call Box 9000, Mayagüez PR 00681-9000