Molecular Spectroscopy of crossed molecular beams and jets; Laser-Raman and surface enhanced Raman Spectroscopy of biomolecules and their interactions with heavy metal ions and carcinogenic compounds; molecular spectroscopy of coordination compounds, superconductors, and explosives; theoretical calculations correlating measured spectroscopic properties.

Representative Publications:

Ion mobility spectrometry determination of smokeless powders on surfaces. Colon, Y.; Ramos, C..; Rosario, S.; Castro, M. E.; Hernandez, S. P.; Mina, N. Center for Chemical Sensor Development for Detection of Explosives, Department of Chemistry, UPR at Mayaguez, Mayaguez, USA. International Journal for Ion Mobility Spectrometry (2002), 5(3), 127-131

Surface enhanced Raman spectroscopy of molecular complexes between DNA and selected PAH. Talavera Ortega, M..; Hernandez, S.P. Department Chemistry, UPR, Mayaguez, P. R. Book of Abstracts, 213th ACS National Meeting, San Francisco, April 13-17 (1997), CHED-486. Publisher: A.C.S., Washington, D. C

Synthesis and Spectroscopic Characterization of Group II-B Complexes of 2,2'-Bipyridine. Hernandez, R..; Vazquez, R.; Martinez, M.; Hernandez, S.P. Department Chemistry, UPR, Mayaguez, P. R. Book of Abstracts, 212th ACS National Meeting, Orlando, FL, August 25-29 (1996), CHED-171. Publisher: A.C.S, Washington, D. C.