Cleaning of direct compression continuous manufacturing equipment through displacement of API residues by excipients
January 22th, 2024 – This research is the first-time effort to clean the direct compression continuous manufacturing (CM) system using only excipients. This cleaning process does not need to dismantle the CM equipment and PAT system. The established PAT system could be used to monitor the displacement of drug residues by excipients. Patel, D. S.;…