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Chemistry Department


Elsie Parés Professor
picture of Elsie Pares


phone: (787) 832-4040 ext. 3146
fax: (787) 265-3849
email: elsie.pares@upr.edu
office: Q-143
website: Not available
Group Members:

Education

Ph.D. Purdue University, 2000

Recognitions

2014 Best Mentor Award, Industrial Biotechnology Student Association (AEBI)
2014 MGM Award, Honorable Sorority Sigma Delta Nu
2013 RCR Award, Honorable Sorority Sigma Delta Nu
2007 Coordinator Award, 31st ACS Senior Technical Meeting
2005 ACS ChemLuminary Award: Education in Chemistry

Teaching Interests

Biochemistry
Biophysical Chemistry
Organic Chemistry

Research Interests

  • VEGF/Insulin/Lysozyme: Biophysical characterization of DNA aptamer:protein complexes for biomedical applications.
  • Transferrin: Interaction of selected anticancer metallocenes dichlorides with apo-human transferrin, a biophysical and molecular docking characterization.
  • NF-IL6: Regulation of the promoter region during macrophage differentiation.
  • FAP1: Determination of its protein structure and function in yeast.
  • SAA: Sequestration of bound proteins to SAA1/2 by co-immunoprecipitation and its characterization through mass spectrometry.
  • Wsc1-3: Biophysical characterization of the cytoplasmic domain of three cell surface proteins that function as stress sensors in yeast.
  • Babesiosis: Identification of small peptides as biomarkers for biosensor applications.

Specific Subjects of Research Interests: Recombinant DNA Technology, Eukaryotic Gene Expression, Bacterial and Cell Culture, Transfection Assay, Electrophoretic Mobility Shift Assay, Western blot, Absorption Spectroscopy, Magnetic Resonance, Bioinformatics, DNA-Protein Interaction, Protein-Protein Interaction, Protein Structure, Protein Function, Biosensor Design

Selected Publications

https://www.ncbi.nlm.nih.gov/myncbi/elsie.pares-matos.1/bibliography/public/

  1. Güette-Fernandez JR, Narváez-Pita X, Meléndez E, Parés-Matos EI. Interaction of metallocene dichlorides with apo-human transferrin: A spectroscopic study and cytotoxic activity against human cancer cell lines. MedCrave JIMBOA. 2020 July 31; 5(3):79-109. NIHMSID: NIHMS1641141.
  2. Heredia FL, Resto PJ, Parés-Matos EI. Fast Adhesion of Gold Nanoparticles (AuNPs) to a Surface Using Starch Hydrogels for Characterization of Biomolecules in Biosensor Applications. Biosensors (Basel). 2020 Aug 14;10(8). doi: 10.3390/bios10080099. PubMed PMID: 32824022; PubMed Central PMCID: PMC7460011.
  3. Vélez-Segarra V, Carrasquillo-Carrión K, Santini-González JJ, Ramos-Valerio YA, Vázquez-Quiñones LE, Roche-Lima A, Rodríguez-Medina JR, Parés-Matos EI. Modelling and molecular docking studies of the cytoplasmic domain of Wsc-family, full-length Ras2p, and therapeutic antifungal compounds. Comput Biol Chem. 2019 Feb;78:338-352. doi: 10.1016/j.compbiolchem.2019.01.001. Epub 2019 Jan 3. PubMed PMID: 30654316; PubMed Central PMCID: PMC6377308.
  4. Güette-Fernández JR, Meléndez E, Maldonado-Rojas W, Ortega-Zúñiga C, Olivero-Verbel J, Parés-Matos EI. A molecular docking study of the interactions between human transferrin and seven metallocene dichlorides. J Mol Graph Model. 2017 Aug;75:250-265. doi: 10.1016/j.jmgm.2017.05.005. Epub 2017 May 30. PubMed PMID: 28609757.