portico

BioOrganometallic and BioInorganic Chemistry Research Group

Publications


Latest Publications

 “Crystal structure of 16-ferrocenemethyl-3β-Hydroxyestra-1,3,5(10)-trien-17-one: a potential chemotherapeutic drug” José A. Carmona-Negrón, Mariola M. Flores-Rivera, Zaibeth Díaz-Reyes, Curtis E. Moore, Arnold L. Rheingold and Enrique Meléndez.  Acta Cryst. 2016, E72, 868-871.

 “New Platinum(II) Complexes with Benzothiazole Ligands” Jose´ A. Carmona-Negrón, Mayra E. Cádiz, Curtis E. Moore, Arnold L. Rheingold and Enrique Meléndez.  Acta Cryst. 2016, E72, 412–416.

 “Molybdocene dichloride intercalation into zirconium phosphate nanoparticles” Barbara Casañas-Montes,Agustín Díaz,Cindy Barbosa,Coralis Ramos,Cindy Collazo,Enrique Meléndez, Clémence Queffelec,Franck Fayon,Abraham Clearfield,Bruno Bujoli,and Jorge L. Colón. J. Organometal. Chem. 2015, 791, 34-40.

” Nanostructured gold dsDNA sensor for early detection of breast cancer by beta protein 1 (BP1)” Wanda I. Pérez, Yarelis Soto, Jaime- E. Ramirez-Vick, Enrique Meléndez. J. Electroanal. Chem 2015, 751, 49-56.

 “Crystal structure of bis[4-(1H-pyrrol-1-yl)phenyl]ferrocene-1,1’-dicarboxylate: a potential chemotherapeutic drug” Wanda I. Pérez, Arnold L. Rhengold, Enrique Meléndez, Acta Cryst. 2015, E71, 536-539.

 “Ferrocenes as potential chemotherapeutic drugs: Synthesis, cytotoxic studies and micronucleus assay” Wanda I. Pérez, Yarelis Soto, Carmen Ortíz, Jaime Matta, Enrique Meléndez, Bioorg. Med. Chem. 2015, 23, 471-479.

 “DNA electrochemical biosensor for metallic drugs at physiological pH” Angel J. Santiago-Lopez, Jose L. Vera, Enrique Meléndez, J. Electroanal. Chem. 2014, 731, 139-144.

 “The addition of Pregnenolone Group Enhances the Anticancer Properties of Titanocene Dichloride in a MCF-7 Xenograft Model” G. Ramos, Y. Loperena, G. Ortiz, A. Szeto, J. Vera, J. Velez, J. Morales, D. Morrero, L. Castillo, S. Dharmawardhane, E. Meléndez, A.V. Washington, Anticancer Research 2014, 34(4):1609-15.

 “Water soluble molybdenocene complexes: Synthesis, cytotoxic activity and binding studies to ubiquitin by fluorescence spectroscopy, circular dichroism and molecular modeling” Xiomara Narváez-Pita, Carlos Ortega-Zuniga, Claudia Y. Acevedo-Morantes, Belinda Pastrana, Jesús Olivero-Verbel, Wilson Maldonado-Rojas, Jaime E. Ramírez-Vick and Enrique Meléndez, J. Inorg. Biochem. 2014, 132, 77–91.

“Functionalized ferrocenes: The role of the para substituent on the phenoxy pendant group” JoséL. Vera, Jorge Rullán, Natasha Santos, Jesús Jiménez, Joshua Rivera, Alberto Santana, Jon Briggs, Arnold L. Rheingold, Jaime Matta and Enrique Meléndez, J. Organometal. Chem. 2014, 749, 204-214.

”New tungstenocenes containing 3-hydroxy-4-pyrone ligands:  Antiproliferative activity on HT-29 and MCF-7 and binding studies to human serum albumin by fluorescence spectroscopy and molecular modeling methods” Moralba Domínguez-García, Carlos Ortega-Zúñiga and Enrique Meléndez, J. Biol. Inorg. Chem. 2013, 18, 195-209.

“Bioorganometallic Chemistry of Molybdenocene Dichloride and Its Derivatives” Enrique Meléndez, Review Article, J. Organometal. Chem. 2012, 706-707, 4-12.

“Metallocenes as target specific drugs for cancer treatment” Enrique Meléndez, Review Articule, special issue on Metals in Medicine, Inorg. Chim. Acta 2012, 393. 36-52.

“Cytotoxicity and Reactive Oxygen Species Generated by Ferrocenium and Ferrocene on MCF7 and MCF10A Cell Line” Claudia Y. Acevedo-Morantes, Enrique Meléndez, Suriner P. Singh, Jaime E. Ramírez-Vick,Journal Cancer Science and Therapy2012 4(9), 271-275.

“Synthesis, characterization and cytotoxic studies of water soluble [(η5-C5H5)2 Mo(thionucleobase/thionucleoside)]Cl complexes in breast and colon cancer cell lines” Debora Acevedo-Acevedo, Jaime Matta and Enrique Meléndez. J. Organometal. Chem. 2011 , 696, 1032.

” Host-Guest Interactions between Calixarenes and Cp2NbCl2” Alexis Morales, Alberto Santana, Gerhard Althoff, Enrique Melendez. J. Organometal. Chem. 2011 696, 2519.

” Poly(pyrrole-N-ferrocene-pyrrole) copolymer based mediator free glucose biosensor” Netzahualcóyotl Palomera, José L. Vera, Enrique Meléndez, Jaime Ramirez-Vicks, Sunil K. Arya and Surinder P. Singh. J. Electroanal. Chem. 2011,658, 33.

“Vectorized ferrocenes with estrogens and vitamin D2: synthesis, cytotoxic activity and docking studies” José Vera,Li Ming Gao,Alberto Santana,Jaime Mattaand Enrique Meléndez.  Dalton Trans. 2011, 40, 9957.

”Titanium(IV) Complexes : Cytotoxicity and Cellular Uptake of Titanium(IV) Complexes on Caco-2 Cell Line”  Ramón Hernández, Janet Méndez, José Lamboy, Madeline Torres, Féliz R. Román and Enrique Meléndez. Toxicology in Vitro 2010, 24, 178-183.

“Cytotoxic properties of titanocenyl amides on breast cancer cell line MCF-7” Li Ming Gao and Enrique Meléndez. Metal-Based Drugs 2010 Article ID 286298, doi:10.1155/2010/286298.

 “Synthesis and Cytotoxicity Studies ofSteroid-Functionalized  Titanocenes as Potential Anticancer Drugs: Sex Steroids as Potential Vectors for Titanocenes”  Li Ming Gao, José L. Vera, Jaime Matta and Enrique Meléndez. J. Biol. Inorg. Chem. 2010, 15, 851-859.