RISE E BASE undergraduates must work in the research laboratory of one of the following off-campus research mentors in the summer months.
| Off Campus Research Mentors | Institution | Source of Funding |
| Daniel Colon | Yale University | NSF,NIH |
| Mike Dean | National Cancer Institute-NIH | NIH NCI |
| Juan Rodriguez Flores | Weil Cornell Medical College | QNRF |
| Carlos Rinaldi | University of Florida | two R21; NSF CBET; P&G; |
| Andrew B. Gladden | MD Anderson | NIH |
| Benjamin G.Keselowsky | University of Florida | Pfizer; two RO1 NIDDK; |
| Kevin John Otto | University of Florida | two DARPA; NIH |
| Carmen Cadilla | UPR Medical Sciences Campus | NIH |
| Tanmay P. Lele | University of Florida | NSF; NIH R01 |
| Sharilyn Almodovar | Texas Tech | R21 NIH; |
| Edu Suarez | UPR Ponce | NIH, PRST |
| Cherie Stabler | University of Florida | NIH R01, UC4; Diabetes Foundation |
| Reinhard Laubenbacher | UCONN Health | NIH R01; R25; NSF DMS; US Army |
| Andres Garcia | Georgia Institute of Technology | Three RO1; two R21; one T32; |
| Kyle D. Allen | University of Florida | NIH RO1; NIH T32 |
| Naoko Tanese | NYU School of Medicine | Associate Dean NYU |
| Victor Torres | NYU School of Medicine | four RO1; 1 NIH contract; private |