Paul A. Sundaram, Ph.D
Professor
Office: L-240
paul.sundaram@upr.edu
T: 787-832-4040 x3719, 3661
http://www.me.uprm.edu/sundaram
Education
|
The Ohio State University, Ohio, USA, 1988 |
|
The Ohio State University, Ohio, USA, 1987 |
|
IIT Varanasi, 1984 |
Background
|
Professor, tenured, University of Puerto Rico, Mayagüez, Puerto Rico, Department of Mechanical Engineering, |
|
Adjunct Professor, Purdue University, Lafayette, Indiana, Department of Biomedical Engineering |
|
Chairperson, University of Puerto Rico, Mayagüez, Puerto Rico, Department of Mechanical Engineering |
|
Summer Faculty Research Fellow, NWSC, Dahlgren, VA |
|
Summer Faculty Research Fellow, NWSC, Dahlgren, VA |
|
Summer Faculty Research Fellow, ARL, Aberdeen, MD |
|
Summer Faculty Research Fellow, ARL, Aberdeen, MD |
|
Visiting Scientist, Forschungszentrum Jülich, Jülich, Germany, Institute für Werkstoffe und Verfahren der Energietecknik |
|
Associate Professor, tenured in 1995, University of Puerto Rico, Mayagüez, Puerto Rico, Department of Mechanical Engineering |
|
Assistant Professor, University of Puerto Rico, Mayagüez, Puerto Rico, Department of Mechanical Engineering |
|
Summer Faculty Research Fellow, Argonne National Laboratory, Argonne, Illinois |
|
Graduate Research and Teaching Assistant, The Ohio State University, Columbus, Ohio, Department of Metallurgical Engineering |
Academic and Professional Leadership
|
|
|
|
|
|
|
|
Conference Publications
|
|
|
|
|
|
|
|
|
|
|
|
|
Major Peer-Reviewed Journal Publications
|
|
|
|
|
|
|
|
|
|
|
Awards
|
|
|
|
|
|
|
|
|
|
|
Mechanism of mechanotransduction in connector protein Vinculin under cyclic loads
The connector protein Vinculin is expected to join the actin microfilament and the focal adhesion complex and thus provide mechanical stability to a cell. Earlier observations have indicated the abdication of this role by Vinculin under prolonged cyclic stimulation resulting in increased cell motility. The mechanism by which attachment and detachment occur is being studied in the MCF 10A cell line.
Understanding the directionality and increased expression of collagen in the ECM under mechanical stimulus
The deposition of collagen in the ECM is being studied under the application of a mechanical stimulus in murine osteoblasts. Live cell imaging will be used to determine the mechanism and transport function of collagen vesicles under the effect of varying load applied on the cell substrate. The goal is to grow collagen fibers in preferred orientation though the application of the appropriate mechanical stimulus.