Thermoforesis is a phenomenon that can expand new horizons of what the not too distant future there is the possibility of building machines and nano-scale structures. That is why the importance for engineers and scientist to know how these models behave. In other words it you understand their behavior and properties of these nano machines can be used for applications in areas as diverse as medicine, and medical applications. One possible application for these structures can be used to combat diseases such as cancer, among others. The model proposed use an asymmetric particle to induce autonomous movement, which is generated by the temperature gradient of the reactive part of the particle. In other words using the method of manipulation known as via phoretic motion. However, it is the only method to induce movement of proportion there are other sources such as electrical potential, osmotic pressure, and concentration gradient. Often the colloidal particles are exposed to these phenomena, resulting in the same autonomous movement. Hence the importance of investigating these mathematical models that is the foundation for unimaginable scope of possible applications in the future.

Thermophoresis has shown to be used in a much wider class of colloidal fluids, ranging from micellar, protein, and DNA solutions, to microemulsions and latex particle suspensions. This effort is, in part, driven by the potential design of microreactors, sensors, pumps, separators, transporters, mixers and other types of machines. These recent advancements open up alluring perspectives to exploit thermophoresis as a novel tool in macromolecular fractionation, microfluidic manipulation, and selective tuning of colloidal structures. The current applications for thermal gradients are already exploited by some specifc techniques to selectively control mass transfer in macromolecular solutions or colloidal dispersions.